Thursday, August 1, 2019

Coffee - a health risk?


Coffee is one of the most commonly consumed beverages worldwide. Two thirds of Americans drink at least one cup of coffee a day, with the average consumption at 3.1 cups of coffee per day. In the US that’s 400 million cups of coffee a day or 146 billion cups of coffee per year.



Although that is a lot of beans, we are not even close to being a leader in per capita consumption. Finland comes in first at 12 kg of coffee per person per year with the other scandinavian countries - Sweden, Norway, and Denmark - close behind. The US places a distant 25th at 4.2 kg per person per year.



Which brings up the question as to whether all this coffee is affecting our health.  Is Starbucks vying with fast food as a leading contributor to our country’s declining longevity?



Roasted coffee is a complex mixture of more than 1000 bioactive compounds including caffeine and a number of antioxidants.  For those who drink coffee, it provides more of their daily dietary antioxidants than tea, fruit, and vegetables.



A 2017 analysis of over 200 individual studies documented a health benefit for coffee drinkers and the more cups a day, the greater the reduction in all cause mortality. There was  a decrease in heart disease and cancer as well as a number of neurologic conditions. Decaffeinated coffee was as beneficial as caffeinated coffee in its health impact. 



The longevity benefit (approximately 3% per cup) was greatest for the first four cups but even a fifth and sixth cup added an additional boost. The final numbers are impressive. A 17% reduction in all cause mortality, an almost 20% reduction in cardiovascular disease, and a similar reduction in cancer.



The liver fared even better with a 29% lower risk of non-alcoholic fatty liver disease and a 39% lower risk for liver cirrhosis (scarring). 



As did the brain. Coffee drinkers have a lower rate of developing Parkinson’s disease, a decreased risk of depression, and an amazing 25% decrease in the incidence of Alzheimer’s disease. Interestingly, a single randomized study focused on Parkinsonism, there was an improvement in movement symptoms after just three weeks of two cups of coffee a day.



Even the current diabetic epidemic was impacted positively with a 25% risk reduction.



Athletes have long taken advantage of the improvement in athletic performance with just a single cup of coffee - runners randomized to drink coffee shaved about six seconds per mile off their times while weightlifters could squat more weight. 



What about risks? 



There is a marginal increase in complaints of esophageal reflux (heartburn and indigestion).



Fracture risk is increased in women (only) -  one percent with one cup a day rising to 14% at higher daily intakes.



Interestingly there was one cancer that is statistically more common in regular coffee drinkers - ovarian cancer. The reason is not clear and this may be a statistical blip.



Coffee has a cholesterol raising effect which parallels increasing intake of unfiltered coffee. It is speculated that an oily substance in the bean, removed with a paper filter, is the culprit.  The implications of this observation are uncertain as increasing coffee consumption is not associated with more adverse cardiovascular outcomes, including myocardial infarction.



Coffee should be avoided in pregnancy based on a well documented association with low birth weight, preterm birth, and miscarriage.  Most obstetricians suggest pregnant women limit their caffeine intake to 200 milligrams (one small cup of coffee) a day.



Although most of us have heard about the risk of extra heart beats (palpitations and atrial fibrillation) from too much coffee, data shows the opposite to be true.  Caffeine does not increase the risk of atrial fibrillation. And low doses of caffeine, defined in the study as less than five cups of coffee a day, may even have a protective effect.
Finally, let’s not forget those with insomnia who are especially sensitive to the effects of caffeine.



Where does this leave us? My take aways:



1) If you are pregnant, cut back your coffee.



2) If you have a history of osteoporosis with its increased risk of fractures, cut back on your coffee.



3) Otherwise drink as many cups a day as you’d like, the more the better. We’re not yet at the point of prescribing coffee for specific diseases, but like aspirin it is a readily available, over the counter product, with surprising health benefits.


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